If you have a history of genetic defects in your family or have had (spontaneous) repeated pregnancy losses, you should try to make a preventative genetic diagnosis before implantation (PGD). PGD tests can help you determine the health of your embryos before being implanted during fertility treatment. These can help you increase your chances of completing a healthy pregnancy.
Pre-implantation genetic diagnosis (PGD) is a testing procedure, used to detect unhealthy (sick) embryos before being transferred to your uterus during IVF treatment. Developed in the 1980s, the PGD test is used to detect specific problems of genes or chromosomes of the embryo.
During the early stages of development, the cells of your embryo are analyzed for the detection of genetic abnormalities. By detecting genetic problems before implantation, unhealthy or defective embryos can be eliminated, allowing only healthy embryos to be implanted during fertilization.
Pre-implantation genetic diagnosis is, however, a fairly new technique in fertility treatment. It is only available in major fertility clinics and is recommended for couples with a history of genetic or other life-threatening diseases. Many couples are reluctant to give birth to children for fear of transmitting a dangerous genetic defect. Genetic diseases can often have a major impact on a person's life, causing physical and emotional problems, development or even death. PGD is intended to help couples prevent the transmission of these genetic diseases to their children.
in particular, couples doing PGD tests fall into one of the following 3 categories:
What diseases can GDP detect?
Researchers can now highlight specific chromosomes for certain diseases, including:
There are a number of benefits to using PGD. If you already have a child with a genetic disorder, PGD tests can prevent the transmission of the genetic defect to other children. PGD tests can help limit the number of implant failures or spontaneous abortions because they prevent the use of diseased embryos. Pre-implantation genetic diagnosis (PGD) can also help limit the chances of having twins or multiple pregnancies.
There are some disadvantages of using PGD tests to conceive a child. PGD tests can only be used in vitro fertilization, which is not associated with the highest chance of success for all couples. PGD tests are in conflict with the religious or moral views of certain individuals. Because some embryos will be destroyed, you may feel uncomfortable with the idea of using PGD tests to conceive a child.
How to do it
The technique of pre-implantation genetic diagnosis (PGD) is a rather complex procedure, which requires a highly qualified endocrinologist specialized in reproduction. PGD tests can only be performed when the couple chooses to use IVF. PGD tests can usually be performed relatively quickly to ensure the healthy embryo is implanted in time.
The PGD test procedure involves a number of steps:
Unfortunately, because it is so complicated and unavailable, pre-implantation genetic diagnosis (PGD) is a very expensive procedure. You will need to do in vitro fertilization which generally costs over $ 12,000. PGD testing can be combined with in vitro fertilization for an amount between $ 2,500 - $ 4,000. These procedures are not generally covered by medical insurance